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Код каталога 80071714
CAS NO.104075-48-1
Чистота 96% MDL Номер MFCD06407819
EINEC Molecular FormulaC14H16N2.HCl
Молекулярный вес 248.755
| Товар | Информация |
|---|---|
| Механизм действия | Atipamezole HCl is a selective α₂-adrenergic receptor antagonist. It competitively binds to α₂-adrenergic receptors, reversing the sedative and analgesic effects of α₂-adrenergic agonists such as dexmedetomidine and medetomidine. |
| Пользы | – Primarily used in veterinary medicine to reverse the sedative and analgesic effects of α₂-adrenergic agonists in dogs.<br>- Potential use as an anti-Parkinsonian drug in humans. |
| Побочные эффекты | – Transient hypotension within the first 10 minutes post-injection.<br>- Occasional vomiting, hypersalivation, diarrhea, tremors, excitement, or apprehensiveness.<br>- In rare cases, tachycardia, salivation, atypical vocalization, muscle tremor, increased respiratory rate, uncontrolled urination, and defecation. |
| Противопоказания | – Not for use in dogs with cardiac disease, respiratory disorders, liver or kidney diseases, shock, severe debilitation, or extreme stress.<br>- Contraindicated in dogs with known hypersensitivity to the drug. |
| Меры предосторожности | – Handle with caution to avoid accidental exposure, as it can cause irritation or adverse reactions.<br>- Monitor animals closely for sedation relapse, especially after IV administration of α₂-agonists.<br>- Not recommended for use in breeding, pregnant, or lactating dogs.<br>- Safety not evaluated in dogs under four months of age or weighing less than 4.4 lbs (2 kg). |
| Условия хранения | Store desiccated at room temperature. |
| Обращение и использование | – Avoid direct exposure to skin, eyes, or mouth.<br>- Wash thoroughly with water if accidental exposure occurs.<br>- Use with caution in dogs with cardiovascular diseases. |
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