TEL
+ 86-21-6420 0566
English Synonyms sn-Glycero-3-phosphocholine
Код каталога 80019127
CAS NO.28319-77-9
Чистота 99%
Номер MDLMFCD00063544
EINEC248-962-2
Molecular FormulaC8H20NO6P
Молекулярный вес 257.22
Температура плавления: 118~125°С
| категорию | Подробнее |
|---|---|
| химические свойства | Choline Alfoscerate (L-α-glycerophosphorylcholine) is a choline-containing phospholipid with the molecular formula C8H20NO6P. It is a white to off-white crystalline powder or granules. |
| Физические свойства | Melting point: 168–172°C. It is highly hygroscopic and can turn sticky when exposed to humid air. |
| Фармакологические эффекты | Choline Alfoscerate is used to improve cognitive dysfunction in patients with dementia of neurodegenerative and vascular origin. It is hydrolyzed to choline in the gut, which is a precursor of the neurotransmitter acetylcholine. It has been shown to increase acetylcholine levels in the brain, enhance learning and memory, and improve cognitive, behavioral, and functional outcomes in patients with Alzheimer’s disease and stroke. |
| Механизм действия | It acts as a parasympathetic agent by increasing the release and levels of acetylcholine in the brain. It also promotes neuronal differentiation, antagonizes neurotoxicity, and reduces oxidative stress. |
| Фармакокинетика | It has an elimination half-life of 0.5–6.2 hours. It is completely absorbed following oral administration. |
| Formulations and Administration | Commercially available as soft capsules, typically administered at a dose of 400 mg three times a day. Tablet formulations have also been developed to overcome the disadvantages of soft capsules. |
| Безопасность и меры предосторожности | Generally well-tolerated, but some studies have reported potential risks such as increased stroke incidence in large cohorts. |
| Условия хранения | Хранить в сухом, прохладном месте, защищенном от влаги. |
Отказ от ответственности: приведенный выше контент предназначен только для справки и общения среди инсайдеров отрасли и не гарантирует его точность или полноту. Согласно соответствующим законам и правилам, а также правилам этого веб-сайта, подразделения или лица, которые покупают соответствующие товары, должны получить действительные квалификации и условия квалификации.
Фабрика и отгрузка
