2-гидроксифенилбороновая кислота

Введение

2-Hydroxyphenylboronic acid, also known as o-Hydroxyphenylboronic acid, is a valuable chemical compound with the CAS number 89466-08-0. It is widely used in organic synthesis and biochemical research due to its unique combination of a phenyl ring and boronic acid functional groups. Below is a detailed overview of this compound, presented in a table format for clarity.

химические свойства

2-Hydroxyphenylboronic acid has a molecular formula of C6H7BO3 and a molecular weight of 137.93 g/mol. Its melting point is 178-182°C, and its boiling point is 327.3±44.0°C. The compound has a density of 1.3±0.1 g/cm³ and appears as a white to light yellow to light orange powder or crystal. It is slightly soluble in water but soluble in organic solvents. The compound should be stored in an airtight, cool, dry place.

Приложения

This compound is widely used in organic synthesis as a versatile reagent for introducing hydroxy and boronic acid moieties into different molecules. It is also used in biochemical research as a tool for studying biomolecular interactions and biological reaction mechanisms. Additionally, 2-Hydroxyphenylboronic acid is a key intermediate in the preparation of pharmaceuticals and agrochemicals. Its ability to form boronate esters makes it an important intermediate in various reactions, such as Suzuki cross-coupling reactions.

Информация по технике безопасности

When handling 2-Hydroxyphenylboronic acid, it is important to follow proper safety procedures. The compound is classified as an irritant to the eyes, respiratory system, and skin (R36/37/38). Appropriate precautions, such as wearing protective clothing, gloves, and eyewear, should be taken. In case of contact with eyes, immediate rinsing with plenty of water and seeking medical advice are recommended (S26).

Поставщики

Several suppliers offer 2-Hydroxyphenylboronic acid in various package sizes, including 1g, 5g, 25g, 100g, 1kg, 5kg, and 25kg. This allows researchers to purchase the quantity that best suits their needs.

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Фабрика и отгрузка