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РазделПодробнееChemical Name & StructureThe compound is (3-Fluoro-4′-Methyl-[1.1′-Biphenyl]-4-yl) Boric Acid, with a chemical formula of C₁₃H...
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Chemical Name & Structure | The compound is (3-Fluoro-4′-Methyl-[1.1′-Biphenyl]-4-yl) Boric Acid, with a chemical formula of C₁₃H₁₁FBO₂. It features a biphenyl core with fluorine substitution at the 3-position and a methyl group at the 4′-position, linked to a boronic acid group at the 4-position. |
Физико-химические свойства | This compound exhibits properties typical of boronic acids, including the ability to form reversible covalent bonds with diols. The presence of fluorine and methyl groups influences its solubility, reactivity, and electronic structure, making it a versatile intermediate in organic synthesis. |
Методы синтеза | It can be synthesized via cross-coupling reactions, such as the Suzuki-Miyaura reaction, using appropriate aryl halides or triflates as starting materials. The boronic acid group is introduced through palladium-catalyzed coupling, ensuring high efficiency and selectivity. |
Приложения | The compound is primarily used in organic synthesis as a building block for pharmaceuticals, agrochemicals, and functional materials. Its unique structure allows for selective functionalization and incorporation into complex molecular architectures. It also finds applications in medicinal chemistry for the development of drug candidates targeting specific biological pathways. |
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