4-этилфенилбороновая кислота

4-этилфенилбороновая кислота, also known asp-Ethylphenylboronic acid, is an organoboron compound with an ethyl substituent at the 4-position of the phenyl ring and a boronic acid group. This compound is a versatile building block in organic synthesis, material science, and pharmaceutical research due to its unique reactivity and structural properties.

Свойства ключа

Синтез

4-этилфенилбороновая кислотаcan be synthesized using various methods, primarily involving organic lithium reagents or Grignard reagents. One specific approach involves using 4-bromophenylacetone as the starting material, which undergoes carbonyl protection, Grignard reaction, and dihydroxyboron substitution to yield 4-ethylphenylboronic acid.

Приложения

В органическом синтезе4-этилфенилбороновая кислотаis a crucial intermediate for preparing complex molecules, especially those requiring defined stereochemistry and functionality. It is widely used in Suzuki coupling reactions, which are essential for forming carbon-carbon bonds in organic synthesis.

The compound is also used in the synthesis of various drug intermediates, such as 4-ethylbiphenylboronic acid, highlighting its importance in pharmaceutical research. Additionally, it serves as an intermediate in the synthesis of liquid crystal materials, showcasing its potential in advanced material applications.

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