4-Пентилфенилбороновая кислота

4-Пентилфенилбороновая кислота, also known asp-Pentylphenylboronic acid, is an organoboron compound with a pentyl substituent at the 4-position of the phenyl ring and a boronic acid group. This compound is a valuable building block in organic synthesis, material science, and pharmaceutical research due to its unique reactivity and structural properties.

Свойства ключа

Синтез

4-Пентилфенилбороновая кислотаcan be synthesized using various methods, primarily involving organic lithium reagents or Grignard reagents. One specific approach involves using 4-bromophenylacetone as the starting material, which undergoes carbonyl protection, Grignard reaction, and dihydroxyboron substitution to yield 4-pentylphenylboronic acid.

Приложения

В органическом синтезе4-Пентилфенилбороновая кислотаis a crucial intermediate for preparing complex molecules, especially those requiring defined stereochemistry and functionality. It is widely used in Suzuki coupling reactions, which are essential for forming carbon-carbon bonds in organic synthesis.

The compound is also used in the synthesis of various drug intermediates, highlighting its importance in pharmaceutical research. Additionally, it serves as an intermediate in the synthesis of liquid crystal materials, showcasing its potential in advanced material applications.

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