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Код каталога 80017148
CAS NO.65899-73-2
Чистота 98%
Номер MDLMFCD00057276
EINEC Molecular FormulaC16H13Cl3N2Os
Молекулярный вес 387.7112
Температура плавления: 78~80°С
| Аспект | Подробнее |
|---|---|
| Механизм действия | Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. It interferes with the production of ergosterol, an essential component of fungal cell membranes, leading to increased cellular permeability and ultimately killing the fungus. |
| Клинические применения | Tioconazole is used to treat various fungal infections, including vaginal yeast infections, ringworm (tinea corporis), athlete’s foot (tinea pedis), jock itch (tinea cruris), tinea versicolor, and cutaneous candidiasis. |
| Лекарственные формы | Available as vaginal ointments, creams for topical application, and suppositories. The vaginal ointment is typically used for 1 to 3 days, while topical creams are applied once or twice daily for up to 7 days. |
| Условия хранения | Should be stored at room temperature, between 68°F to 77°F (20°C to 25°C) in a cool, dry place. |
| Побочные эффекты | Common side effects include mild vaginal burning, itching, or irritation. Other possible side effects are headache, drowsiness, hives, upper respiratory infection, and temporary skin redness or irritation when used topically. |
| Взаимодействия | Tioconazole may interact with other medications, especially those metabolized by the cytochrome P450 system. It is important to inform healthcare providers of all medications being taken. |
| Противопоказания | Tioconazole is contraindicated in individuals with a history of hypersensitivity to the drug or its components. It should not be used during the first trimester of pregnancy. |
| Исследования и разработки | Tioconazole was patented in 1975 and approved for medical use in 1982. It is marketed under various brand names, including Vagistat-1 and Trosyd. |
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