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Carboxymethylglucanis a water-soluble polysaccharide derived from natural yeast glucan extracted from the cell walls ofSaccharomyces cerevisiae, which is then modified by carboxymethylation. It has a special triple ultra-micro spiral structure and acts as a natural and effective immune system regulator.
CAS-9044-05-7
Каталог 164071
| Объект | Подробнее |
| Химическое название | Carboxymethylglucan |
| Номер по CAS | There are multiple carboxymethylglucan – related compounds, and the CAS number can vary depending on factors such as the degree of substitution and the source of the glucan. For example, carboxymethyl – β – 1,3 – glucan may have a different CAS number compared to carboxymethyl – α – glucan. Precise CAS number determination requires more specific information about the structure. |
| Молекулярная формула | Glucan is a polysaccharide composed of glucose monomers. When carboxymethyl groups (-CH₂COOH) are added, the formula becomes more complex. If the glucan has ‘x’ glucose units and ‘y’ carboxymethyl substitution groups, the general formula could be approximated as (C₆H₁₀O₅)ₓ(CH₂COOH)ᵧ. The exact formula depends on the type of glucan (linear or branched, α – or β – linked glucose units) and the degree of substitution. |
| Молекулярная масса | The molecular weight of carboxymethylglucan depends on the number of glucose units and the degree of carboxymethyl substitution. Each glucose unit has a molecular weight of approximately 162 g/mol, and the carboxymethyl group has a molecular weight of about 59 g/mol. So, the molecular weight \(M = 162x+59y\) g/mol, where ‘x’ is the number of glucose units and ‘y’ is the number of carboxymethyl groups. This can range from a few hundred to several thousand daltons or more, depending on the size of the glucan chain and the extent of substitution. |
| Молекулярная структура | The glucan backbone consists of glucose monomers linked together. The type of linkage (α – or β – glycosidic bond) determines the overall structure of the glucan chain. Carboxymethyl groups are attached to the hydroxyl groups of the glucose units. This substitution can occur at different positions on the glucose ring (e.g., C – 2, C – 3, or C – 6), and the degree of substitution can vary. The presence of carboxymethyl groups imparts anionic properties to the molecule due to the acidic nature of the carboxyl group. |
| Внешний вид | It typically appears as a white to off – white powder. The powder may have a fine or granular texture, depending on the preparation method and the degree of aggregation. |
| Растворимость | Carboxymethylglucan is generally more soluble in water compared to native glucan. The carboxymethyl groups increase the hydrophilicity of the molecule. The solubility can be further enhanced at appropriate pH values, as the carboxyl groups can ionize. It may also show some solubility in polar organic solvents, especially those that can interact with the hydrophilic groups on the molecule, such as lower – molecular – weight alcohols. However, solubility in non – polar organic solvents is poor. |
| Функция в промышленности | Биомедицинские приложения: Лечение раны: It can promote wound healing. The anionic nature of carboxymethylglucan can interact with proteins and cells in the wound area, enhancing cell adhesion and migration. It may also have immunomodulatory properties, stimulating the immune system to help in the wound – healing process. Доставка лекарств: Can be used as a drug – delivery carrier. The hydrophilic nature allows for the encapsulation of hydrophilic drugs, and the anionic groups can be used for electrostatic interactions with other molecules or surfaces. Косметика: In cosmetics, it functions as a humectant, helping to retain moisture in the skin. It can also improve the texture and stability of cosmetic formulations, acting as a thickening and stabilizing agent. Пищевая промышленность: Used as a food additive. It can act as a stabilizer, thickener, or emulsifier in food products. For example, in dairy products, it can help prevent separation and improve the consistency. |
| Стабильность | Stable under normal storage conditions, typically at room temperature in a dry place. However, it can be sensitive to extreme pH values. At low pH, the carboxyl groups may protonate, which can affect the solubility and properties of the molecule. At high pH, there may be potential for hydrolysis of the glucan backbone or reactions involving the carboxyl groups. The presence of certain enzymes can also lead to degradation of the glucan chain. In formulations, appropriate pH – buffering agents and preservatives may be added to enhance stability. |
| Вопросы безопасности | In general, carboxymethylglucan is considered safe for use in the concentrations typically used in various industries. In the food and cosmetic industries, it has a good safety profile. However, as with any chemical, some individuals may be sensitive or allergic to it. In industrial settings, proper handling procedures should be followed to avoid inhalation of dust (if in powder form) and contact with eyes and skin. |
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