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CAS № 137-16-6
Лауроилсаркозинат натрия Применение: пищевая промышленность, медицина, сельское хозяйство
| Атрибут | Подробнее |
|---|---|
| Химическое название | Натрий Лауроил Саркозинат |
| Синонимы | N-Lauroylsarcosine Sodium Salt, Sodium N-lauroylsarcosinate |
| Номер по CAS | 137-16-6 |
| Формула | C15H28NNaO3 |
| Молекулярная масса | X |
| Внешний вид | White to pale yellow liquid or powder |
| Растворимость | Soluble in water, ethanol, and glycerol |
| Приложения | Used as a foaming and cleansing agent in shampoo, toothpaste, shaving foam, and other personal care products; also used in metal processing, lubrication, and as a food additive |
| Биологическая активность | Mild and biodegradable anionic surfactant; enhances hair appearance and feel; reduces skin irritation caused by traditional surfactants |
| Условия хранения | Хранить в сухом, прохладном месте, вдали от прямых солнечных лучей и несовместимых материалов. |
| Информация по технике безопасности | Approved by FDA as an indirect food additive; CIR approved for use in rinse-off products; generally recognized as safe for intended uses |
Имена и идентификаторы
| Имя | sodium N-lauroylsarcosinate |
| Синонимы | GARDOL Sarkosyl N-Methylglycinol Lauryl sarcosine sodium Sodium laurylsarcosinate N-dodecyl-N-methylglycine Sodium N-lauryl sarcosine Лауроилсаркозинат натрия Sodium N-lauroyl sarcosine НАТРИЯ ЛАУРОИЛСАРКОЗИНАТ N-LAUROYLSARCOSINE NA-SALT Sodium N-laurylsarcosinate Sodium N-dodecylsarcosinate sodium N-lauroylsarcosinate N-лауроил саркозинат натрия LAUROYLSARCOSINE, SODIUM SALT Натриевая соль N-лауроилсаркозина N-LAUROYLSARCOSINE SODIUM SALT N-Dodecylsarcosine, sodium salt N-LAURYL SARCOSINE, SODIUM SALT Sarcosine, N-dodecyl-, sodium salt Sodium N-dodecyl-N-methylglycinate sodium [dodecyl(methyl)amino]acetate N-LAUROYLSARCOSINE SODIUM SALT HYDRATE sodium [dodecanoyl(methyl)amino]acetate sodium 2-(decanoyl-methyl-amino)acetate Glycine, N-dodecyl-N-methyl-, sodium salt n-methyl-n-(1-oxododecyl)glycine sodium salt |
| CAS | 137-16-6 7631-98-3 |
| EINECS | 205-281-5 |
137-16-6 – Физико-химические свойства
| Молекулярная формула | C15H28NO3.Na |
| Молярная масса | 293.38 |
| Плотность | 1.033 г/м при 20°C |
| Температура плавления | 46 ° C |
| Точка возгорания | 267 ℃ |
| Растворимость воды | Растворим в воде (293 г / л). |
| Растворимость | It’s hygroscopic. Soluble in aqueous alcohol solutions such as water, ethanol or glycerol. |
| Давление пара | 0.02 гПа (20 °C) |
| Внешний вид | Белый порошок |
| Удельный вес | 1.03 (20/4℃) |
| Цвет | Белый |
| Максимальная длина волны (λmax) | ['λ: 260 нм Aмакс: 0.2', , 'λ: 280 нм Aмакс: 0.06'] |
| Merck | 14,4368 |
| BRN | 5322974 |
| PH | 7.0-9.0 (25 ℃, 1M в H2O) |
| Условия хранения | комнатная температура |
| Стабильность | Стабильная. Несовместим с сильными окислителями. |
| чувствительный | гигроскопический |
| MDL | MFCD00042728 |
| Используйте | It is an anionic surfactant, especially suitable for the preparation of shampoo, Bath, facial cleanser, baby detergent, dishwashing detergent, etc. |
137-16-6 – Риск и безопасность
| Коды рисков | R36/37/38 – Раздражает глаза, дыхательную систему и кожу. R41 – Опасность серьезного повреждения глаз. R38 – Раздражает кожу R23 – Toxic by inhalation |
| Описание безопасности | S22 – Не вдыхайте пыль. S24/25 – Избегать контакта с кожей и глазами. S36/37/39 – Носите подходящую защитную одежду, перчатки и средства защиты глаз/лица. S27 – Немедленно снимите всю загрязненную одежду. S26 – При попадании в глаза немедленно промыть большим количеством воды и обратиться к врачу. S45 – В случае несчастного случая или плохого самочувствия немедленно обратитесь к врачу (по возможности покажите этикетку). S38 – In case of insufficient ventilation, wear suitable respiratory equipment. S37/39 – Носите подходящие перчатки и средства защиты глаз/лица. |
| Идентификаторы ООН | UN 2811 6.1 / PGII |
| WGK Германия | 3 |
| RTECS | MC0598960 |
| F-КОДЫ МАРКИ FLUKA | 3-10 |
| ЗКТВ | Да |
| Код ТН ВЭД | 34021190 |
| Класс опасности | 6.1 |
| Группа упаковки | II |
| Токсичность | LD50 перорально у кроликов: 2888 мг/кг |
137-16-6 – Добывающая и перерабатывающая промышленность
| сырье | Фосфор трихлорид Лауриновая кислота |
Справочная информация
| LogP | 0.37 |
| введение | sodium lauryl sarcosine, English name is SODIUM LAUROYL SARCOSINATE, alias: sodium lauryl-N-methylaminoacetate, sodium dodecyl-N-methylglycine. Sodium lauryl sarcosine is mainly used in cosmetics and skin care products as antistatic, foaming agent, detergent and surfactant. The risk coefficient is 3. It is relatively safe and can be used with confidence. It generally has no effect on pregnant women. Sodium lauryl sarcosine has no acne-causing properties. FDA approves sodium lauryl sarcosine as a direct food additive, and CIR allows it to be used in rinse products and resident products at concentrations not exceeding 5%. |
| эффект | Sodium lauryl sarcosine is a foaming agent and surfactant, it is lauryl sarcosine salt (made from creatine or caffeine decomposition), a modified fatty acid. It is often used as a foaming agent, surfactant and hair conditioner in shampoo, shower gel, facial cleanser and shaving products. |
| приложению | sodium N-laurophthalein myosinate is an anionic amino acid surfactant with low toxicity, low irritation, good biodegradability, better compatibility, antibacterial and corrosion resistance, etc, widely used in daily chemicals, food, metal processing, mineral flotation, pesticide deployment, biomedicine and many other fields |
| безопасность | sodium lauryl sarcosine can be found in the cosmetics database as a moderately dangerous ingredient, mainly because it may contain impurity nitrosamines (nitrosamine, a well-known carcinogen), and because it is considered as a penetration aid, it can change the skin structure and help other chemicals penetrate deep into the skin. CosmeticsInfo.org believes that sodium lauryl sarcosine should not be used in cosmetics and personal care products because it may form nitroso (N-nitroso) compounds. Sodium lauryl sarcosine does not have the potential toxicity and harm expected, and it is orally low-toxic. It was not found to be mutated, irritating or allergenic. However, as mentioned earlier, it can promote other ingredients to penetrate the skin. |
| метод синтеза | 1) synthesis of lauroyl chloride: add a certain amount of lauric acid into a dry three-mouth flask equipped with a reflux condenser, heat and melt, control the temperature at 60 ~ 70e, slowly add phosphorus trichloride dropwise under full stirring, react for 2 hours, let stand for stratification, remove the phosphorous acid in the lower layer, and obtain the upper layer of lauroyl chloride. 2) Synthesis of N-lauroyl sarcosine: Add a certain amount of sodium sarcosinate solution and solvent tetrahydrofuran to a four-mouth flask with an electric stirrer and a reflux condenser, and add lauroyl chloride and sodium hydroxide aqueous solution dropwise under stirring. The pH value of the reaction system is controlled within the range of 9~11. After the dropwise addition is completed, continue to react for 3 hours to recover the solvent, use dilute acid to adjust the pH value to 1~2 to convert sodium N-lauryl sarcosine into water-insoluble N-lauryl sarcosine, thereby separating from water-soluble inorganic salt impurities. Use ether to extract the product, wash the upper oil layer to neutral, dry anhydrous sodium sulfate, evaporate the solvent, and recrystallize with petroleum ether to obtain white needle-like crystals. |
| использование | sodium dodecyl sarcosine is an amino acid surfactant. in addition to excellent surface activity, it also has the characteristics of antibacterial, bactericidal, corrosion and rust inhibition, and good biodegradability. therefore, it is widely used in many fields such as detergents, cosmetics, food and beverages, metal rust prevention, mineral flotation, pesticides and biomedicine. Biochemical research. Anionic surfactant. Hexokinase inhibitors. Anionic detergent. Isolation of yeast ribonucleic acid. It can be used for RNA and DNA segregation, as a dissolving agent in cell purification, an additive when separating DNA from human serum, and can also increase the nitrogen fixation ability of legume rhizobia by adding this product. There are also many applications in immunochemistry An anionic surfactant. Since it does not produce excessive foam, it can be used for cell lysis in RNA extraction schemes. Relevant scholars have established an analytical method for the determination of sodium dodecyl sarcosinate by gas chromatography. Using dodecyl acid as internal standard, the sample reacts with boron trifluoride methanol solution to generate methyl ester compound, HP-5 chromatographic column is used as analytical column, FID is used as detector, and the internal standard method is used for quantification. |
| Способ производства | The sarcosine aqueous solution plus sodium hydroxide is prepared by reacting with lauroyl chloride under alkaline conditions. |
Фабрика и отгрузка
