TEL
+ 86-21-6420 0566
Код каталога 80017813
CAS NO.15307-79-6
Чистота 98%
Номер MDLMFCD00082251
EINEC239-346-4
Molecular FormulaC14H10Cl2NNaO2
Молекулярный вес 318.1305
Точка плавления: 279~289℃.
| Аспект | Подробнее |
|---|---|
| Механизм действия | Diclofenac sodium is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits both cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, thereby reducing the synthesis of pro-inflammatory prostaglandins. It also down-regulates sensitized peripheral pain receptors by stimulating the L-arginine/nitric oxide (NO)/cGMP pathway. |
| Фармакокинетика | Diclofenac sodium is rapidly absorbed when administered orally and reaches peak plasma concentrations within 1 to 2 hours. It is highly protein-bound (99%) and has a half-life of approximately 1 to 2 hours. The drug is metabolized in the liver and excreted mainly in the urine. |
| Администрация | Available in various forms, including oral tablets, suspension, intramuscular injection, intravenous injection, transdermal gel, and rectal suppositories. For acute pain, intravenous bolus injections can be administered. |
| Побочные эффекты | Common side effects include gastrointestinal upset, nausea, vomiting, and abdominal pain. Prolonged use may lead to gastrointestinal ulcers, bleeding, and renal impairment. |
| Условия хранения | Diclofenac sodium should be stored at room temperature (15° to 30°C) and protected from light. |
| Особые соображения | Use with caution in patients with a history of gastrointestinal ulcers, renal impairment, or cardiovascular disease. Concurrent use with other NSAIDs or anticoagulants may increase the risk of adverse effects |
Отказ от ответственности: приведенный выше контент предназначен только для справки и общения среди инсайдеров отрасли и не гарантирует его точность или полноту. Согласно соответствующим законам и правилам, а также правилам этого веб-сайта, подразделения или лица, которые покупают соответствующие товары, должны получить действительные квалификации и условия квалификации.
Фабрика и отгрузка
